David Gottlieb Yuengling founded the eponymous brewery in 1829 that eventually became both the largest domestically-owned brewery in America and also the oldest. From its location in Pottsville, Pennsylvania, roughly 90 miles northwest of Philadelphia, D.G. Yuengling was able to serve the thousands of miners working in the relatively remote coal and slate belt regions of Eastern Pennsylvania, along with the booming towns that sprung up around them.